It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. A single copy of these materials may be reprinted for noncommercial personal use only. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Advertising revenue supports our not-for-profit mission. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. You can take your doses either before or after meals. Take this medication by mouth as directed by your doctor, usually twice a day. Is it safe to drive while on this medicine? Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Natural Medicines. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). You need to take it every day in order for it to work. 8.0 out of 10 from a total of Call your doctor for medical advice about side effects. Do not share this medication with others. Are you looking for information on isosorbide dinitrate (Isordil) instead? Properly discard this product when it is expired or no longer needed. Consult your doctor before breast-feeding. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. What special dietary instructions should I follow? Saw palmetto. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). The extended-release tablet usually is taken once daily in the morning. Select a condition to view a list of medication options. Medicines containing Isosorbide Mononitrate. Accessed Sept. 7, 2022. The most common side-effect is headache. May also be prescribed off label for Esophageal Spasm. Using this medicine with any of the following medicines is not recommended. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. Does isosorbide mononitrate (Monoket) affect your kidneys? Avoid combinations; the risk of the interaction outweighs the benefit. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Thirty percent of the patients never experienced headache from the given dosages. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. If you have recently had a head injury or a heart attack. Canada residents can call a provincial poison control center. Usually avoid combinations; use it only under special circumstances. Consult your doctor for more details. Read our editorial policy. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. eCollection 2021. You may report side effects to the FDA at 1-800-FDA-1088. Zhonghua Yi Xue Za Zhi (Taipei). Some don't work well with prescription medicines. View more. Some side effects may occur that usually do not need medical attention. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Herbal supplements are natural, so they must be safe, right? A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. These side effects may go away during treatment as your body adjusts to the medicine. Copyright 2023 IBM Watson Health. In: Current Medical Diagnosis & Treatment 2022. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. This document does not contain all possible drug interactions. It works and leaves the body quickly, so it needs to be taken twice a day. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. Does isosorbide mononitrate (Monoket) lower blood pressure? Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Learn to reduce stress through mindful living. If headaches continue or become severe, tell your doctor promptly. Accessed Sept. 7, 2022. Take the missed dose as soon as you remember it. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. 7.6 out of 10 from a total of Ask your doctor before using aspirin together with alcohol. 1998 Oct;61(10):577-83. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. Now, youll enjoy a streamlined experience created specifically for healthcare providers. 2023 eHealthMe.com. 19 are major, 174 are moderate, and 2 are minor. If you have any questions about this medicine ask your pharmacist. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. In the US - Call your doctor for medical advice about side effects. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. B complex. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Even if the medication is working, you may experience some unwanted side effects. Licorice. Does Viagra add to the risks of melanoma? 88 ratings on Drugs.com. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. These side effects may go away during treatment as your body adjusts to the medicine. Journals of the American College of Cardiology. Never take more than the prescribed dose. This should pass after a few days. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Natural Medicines. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. Isosorbide mononitrate helps to prevent angina chest pain from developing. tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). My EKG showed Assess your symptoms online with our free symptom checker. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. . Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. Accessed Sept. 7, 2022. government site. To use the sharing features on this page, please enable JavaScript. Prescription and OTC Although not all of these side effects may occur, if they do occur they may need medical attention. Generic alternatives may be available. It will not treat an angina attack that has already begun. What special precautions should I follow? With any medication, there are risks and benefits. WebMD does not provide medical advice, diagnosis or treatment. Drug information provided by: IBM Micromedex. Keep all medications away from children and pets. Mehta D. Botanical medicines. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. information and will only use or disclose that information as set forth in our notice of Many people using this medication do not have serious side effects. See the full pregnancy warnings document. Higher dosages are associated with stomach irritation and Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. Of the total drug interactions, Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). tell your doctor and pharmacist if you are allergic to isosorbide; nitroglycerin tablets, patches, or ointment; any other medications, or any of the ingredients in isosorbide tablets, extended-release tablets, or extended-release capsules. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Do not stop taking isosorbide without talking to your doctor. This is called a medicine interaction. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. If you notice any other effects, check with your healthcare professional. Nitrates in the management of acute coronary syndrome. Clin Res Cardiol. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. The effects of this exposure on a nursing infant are unknown. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Some people feel dizzy or fall when changing positions, such as going from sitting to standing. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Generic alternatives may be available. This is called a medicine interaction. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. You can consult me online for homeopathic treatment. Natural Medicines. Isosorbide mononitrate belongs to the group of medicines called nitrates. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. For details see our conditions. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). An official website of the United States government. Epub 2006 Mar 22. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Journal of the American College of Cardiology. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Cleophas TJ, Niemeyer MG, van Der Wall EE. This content does not have an Arabic version. Unless there is a specific reason you need the brand, the generic medication will be a better value. privacy practices.