Trkyilmaz GG, Rumeli S. Attitude changes toward chronic pain management of pain physicians in Turkey during the COVID-19 pandemic. Rodrguez Y, Vatti N, Ramrez-Santana C, Chang C, Mancera-Pez O, Gershwin ME, Anaya JM. Like many of my own patients, you may be interested in doing more to treat to pain than just relying on medications, but you arent sure where to start. Relevant guidelines from the American Society of Anesthesiologists (ASA), American Society of Regional Anesthesia (ASRA), American Society of Interventional Pain Physicians, and American Academy of Physical Medicine and Rehabilitation, European Pain Federations, and The WHO database on COVID-19 were screened for relevant publications. Rania S. Ahmed: searching, study screening, editing. Shamard Charles, MD, MPH is a public health physician and journalist. Eur J Clin Pharmacol. El-Tallawy SN, Titi MA, Ejaz AA, Abdulmomen A, Elmorshedy H, Aldammas F, Baaj J, Alharbi M, Alqatari A. Ghai B, Malhotra N, Bajwa SJ. Last medically reviewed on February 27, 2023, There are many uncomfortable symptoms associated with asthma. https://doi.org/10.1016/j.jclinepi.2009.06.005. They may have a persistent disability that takes a long time to get through, Altman said. 2020;125(4):4403. The unprecedented pandemic has created a new face of chronic pain post COVID. SN Compr Clin Med. The prevalence of myalgia was higher in hospitalized patients (22.7%) compared to in non-hospitalized patients (16.8%). The COVID-19 pandemic has had unforeseen impacts on the health care services. Int J Ment Health. Yes. Oral or injectable steroids (e.g., used for interventional pain procedures) are immunosuppressive. Increased demand on the health care systems, health care workers, and facilities. We have gotten good at sorting out each patients symptoms and then developing a personalized plan based on our findings.. Its use for costochondritis is off-label, meaning that it is not specifically approved by the Food and Drug Administration (FDA) for that purpose but may help. This program can be updated and used in hard times such as the pandemics to make treatment available and beneficial for such people during COVID as well as post-COVID era. 2014;76:211. 2021;9(6): e884. These steps help to prevent large shifts in blood when a person stands up after lying down. There are publications reporting that radiofrequency denervation is a safe practice in the treatment of interventional pain during the pandemic [125]. Cuthbertson BH, Roughton S, Jenkinson D, Maclennan G, Vale L. Quality of life in the five years after intensive care: a cohort study. any condition that heightens the high risk of complications from COVID, postural orthostatic tachycardia syndrome, New Anschutz Medical Campus clinic will help patients suffering from rare spinal fluid leaks. Fear of infection or the health care facilities get infected. Kosek E, Cohen M, Baron R, et al. Arthralgia is pain in one or more of a persons joints. Intravenous oxycodone versus other intravenous strong opioids for acute postoperative pain control: a systematic review of randomized controlled trials. Pan American Health Organization. This pain may happen. This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors. 2020;176:32552. OKelly B, Vidal L, McHugh T, Woo J, Avramovic G, Lambert JS. Do You Need to Retest After a Positive COVID-19 Result? In addition, some studies showed a strong correlation between the epidural volume and pain relief irrespective of the steroid dose [24, 75]. India, https://doi.org/10.48101/ujms.v127.8794. Breve F, Batastini L, LeQuang JK, et al. One week can be quite normal, but another one terrible. It is a self-limiting condition but needs to be differentiated from more serious causes of chest pain such as a heart attack. It has changed our lives and our approach to medicine. Long Covid may potentially cause chest discomfort. Chronic cardiac problems such as poor exercise tolerance, palpitations, or chest discomfort are among the wide variety of symptoms that are present. What is respiratory syncytial virus (RSV)? Painful HIV-associated sensory neuropathy. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. I could not stand for a long time because I was so weak that even making a standing pose was a challenge. Philippines, Chronic pain is an important health issue and is the most common reason to seek medical care. No funding or sponsorship was received for this study or publication of this article. She is being treated for chest pain, fatigue, and some of her other symptoms both through the specialist long Covid clinic . As the virus causes inflammation and fluid to fill up the air sacs in the lungs, less oxygen can reach the bloodstream. The use of painkillers may also be part of the therapy, regardless of the reason. Iadecola C, Anrather J, Kamel H. Effects of COVID-19 on the nervous system. Nieminen TH, Hagelberg NM, Saari TI, et al. Epub 2020 Jun 11. Peter Abaci, MD, is one of the worlds leading experts on pain and integrative medicine. These factors can be some of the reasons behind your experiencing chest pain post-recovery. Telemedicine plays an important role in consulting physicians and health care providers without unnecessary exposure [9, 16]. 2022;10:2349. https://doi.org/10.3390/healthcare10122349. Telemedicine does not replace clinical practice and the need of face-to-face consultations and patients examination, especially for new patients, rapid changes of the patients condition, or those with associated multiple comorbidities [22, 60, 117]. 2020;161:222935. Collins RA, Ray N, Ratheal K, Colon A. 2021;21(5):6012. Strong opioids may be considered in refractory cases. Published reports indicate that approximately 1020% of COVID-19 patients experience persistent long COVID symptoms from a few weeks to a few months following acute infection [5]. Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study. Pain Ther. Individuals who have recovered from Covid-19 can have symptoms similar to those of a heart attack, including chest pain and occasionally shortness of breath. A phenomenon of protracted immunosuppression, known as PICS (persistent inflammation, immunosuppression, and catabolism syndrome), has been presented as a potential major contributing factor for the presentation of post-COVID symptoms [63]. Pain in COVID Era. Myocarditis detected after COVID-19 recovery. 2012;153:3429. BMJ. PLoS Med. A patient with chronic fatigue will need different services than one with, say, abnormal heart rhythms. Long covid symptoms, in addition to chest discomfort, may include: Specialists are unsure of the exact cause of some patients' protracted covid symptoms. A disorder of the autonomic nervous system, Postural Orthostatic Tachycardia Syndrome - also known as POTS - is usually identified by a rapid increase in the heart rate after getting up from sitting or lying down. Gibbons JB, Norton EC, McCullough JS, et al. Costochondritis, a painful chest pain due to swelling of the cartilage that attaches to the sternum, is a rare post-COVID symptom that some children may experience. 2015;14:16273. The study results suggested that non-invasive stimulation of the auricular branch of the vagus nerve is a possible therapeutic modality for treating long COVID with at least a third of the patients showing improvement, although it is possible that the positive result was simply a placebo response to treatment in the absence of a control group for comparison [134]. Delaying or stopping treatment for patients who are suffering from severe pain will have negative consequences, including increases in pain, disability, and depression. A doctor may prescribe one of several medications to manage angina, including: Severe angina or angina that develops suddenly can require surgical intervention. Management of musculoskeletal pain: an update with emphasis on chronic musculoskeletal pain. Trajectory of long COVID symptoms after COVID-19 vaccination: community based cohort study. When will I be more stable, or should I take MRI for the head and maybe another (heart) diagnosis? But if you have any persistent problems like chest pain, shortness of breath, or feeling faint, those need to be checked out., Get the most popular stories delivered to your inbox monthly, COVID-19 can exacerbate underlying heart conditions, but long COVID symptoms like chest pain and shortness of breath also affect young, previously healthy people. Costochondritis is the inflammation of the cartilages that attach your ribs to the breastbone (sternum). Lichtenstein A, Tiosano S, Amital H. The complexities of fibromyalgia and its comorbidities. UK, Acute COVID-19 infection: Signs and symptoms of COVID-19 for up to 4weeks [1]. Initially right after covid, I only had chest pain, but after having the flu really badly a month later, that might have triggered my long covid and the shortness of breath began. The long-term benefits of telemedicine have been evaluated after 1year post-COVID. To evaluate patients, assess pain, and plan treatment of chronic pain [30]. NPJ Vaccines. Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain. Its an uphill battle, made easier by working with a group of focused specialists like what we have assembled in the Post-COVID clinic at the University of Colorado Hospital.. Influence of lumbar epidural injection volume on pain relief for radicular leg pain and/or low back pain. Headache is one of the most common symptoms during infection, and post-COVID. Urgent: These procedures are time-sensitive; a delay in proceeding would result in significant exacerbation and worsening of the condition. However, pain itself may have an immunosuppressive effect. J Pain Res. 2021. https://doi.org/10.1007/s12016-021-08848-3. Proc (Bayl Univ Med Cent). National Health Service (NHS, 2021): Symptoms lasting weeks or months after the infection has gone [11, 14]. Patient perspective on herpes zoster and its complications: an observational prospective study in patients aged over 50 years in general practice. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Home. It is commonly understood that long-term symptoms can occur regardless of acute infection severity. Case studies have shown that colchicine may be an effective treatment for costochondritis, especially when conventional therapies have failed. Pain. The problem isnt cardiac-specific, she said. (2010). The affected patients complain of muscle pain, tenderness, fatigue, and weakness [43, 67, 110, 111]. Delaying, or stopping, treatment will have negative consequences on chronic pain patients. All authors declare no conflicts of interest. Brain Behav Immun Health. It is a long COVID symptom, meaning it persists for an extended period of time after a person recovers from COVID-19. Xiong Q, Xu M, Li J, et al. Front Physiol. Bileviciute-ljungar I, Norrefalk J, Borg K. Pain burden in post-COVID-19 syndrome following mild COVID-19 infection. Pullen MF, Skipper CP, Hullsiek KH, Bangdiwala AS, Pastick KA, Okafor EC, Lofgren SM, Rajasingham R, Engen NW, Galdys A, Williams DA, Abassi M, Boulware DR. Myocarditis is inflammation of the heart muscle, or myocardium. It has been reported in 2162.5% of the patients according to different meta-analysis studies [67, 105, 106]. The search strategy was restricted to articles that were published between January 2020 and January 2023. Glucocorticoid injections for pain procedures and musculoskeletal pain may interfere with the potency and efficiency of COVID-19 vaccines. Also, the injections of high volumes with lower concentrations of local anesthetics only without steroids. Symptoms that may occur alongside this pain include: Pericarditis causes pleuritic pain that feels better when a person sits up and leans forward. Increased awareness by the pandemic, methods of infection control for the general populations. 2022;377. doi:10.1136/bmj-2021-069676. First double living-donor kidney and liver transplant in the Rocky Mountain region saves life of former Olympic ski jumper, Nurse midwives needed to bridge rural-urban reproductive health care divide. How to protect yourself and others. Comparison of clinical efficacy of epidural injection with or without steroid in lumbosacral disc herniation: a systematic review and meta-analysis. A review of persistent post-COVID syndrome (PPCS). Opioids and corticosteroids used in the treatment of chronic pain and are known to have immunosuppressive effects [9, 20, 125]. According to Dr. Sanchayan Roy, "Treatment of Long Covid Syndrome of chest pain usually involves : a) Assessing the various pulmonary and cardiovascular issues to determine and clinically significant cause of chest pain and treating the root cause. https://doi.org/10.1007/s40122-021-00235-2. All observations demonstrated a high incidence of chronic pain syndromes of various localization in the post- and long-COVID period. COVID-19 is having a profound effect on patients with pain. Globally, with the end of 2022 and the beginning of a new year, the COVID-19 epidemiological update showed that there have been 657,977,736 confirmed cases of COVID-19, including 6,681,433 deaths globally. Niehaus and his colleagues maintain that treating fatigue in long COVID requires addressing problems like inadequate sleep and nutrition; infectious and autoimmune diseases; and heart, lung and nerve disorders. Cardiovascular health: Insomnia linked to greater risk of heart attack. Thanks for the query and description of your symptoms. Zis P, Loannou C, Artemiadis A, Christodoulou K, Kalampokini S, Hadjigeorgiou GM. Copyright 2023, iCliniq - All Rights Reserved, Visit other versions in US, Salah N. El-Tallawy. Mikkelsen ME, Abramoff B. COVID-19: evaluation and management of adults with persistent symptoms following acute illness ("Long COVID"). It is often possible to identify the cause as pleuritic pain, muscular pain, angina, or pain due to heart damage. The exact connection between costochondritis and coronavirus (COVID-19) is unknown. Telemedicine is potentially less accurate in evaluation of the patients condition compared to the conventional in-person visit [16, 22]. Weve seen patients across the board, Altman said. 2018;38(1):1211. explainsDr. Sanchayan Roy,Senior Consultant Internal Medicine and Critical Care,National Heart Institute, Apollo Royal Cradle. 2020;15: e0240784. https://doi.org/10.4103/ija.IJA_652_20. The presence of psychiatric conditions, mental health problems, and occupational and social situations should be taken into consideration during the management of post-COVID pain [25]. Treatment guidelines recommend simple analgesics (e.g., paracetamol) and non-steroidal anti-inflammatory drugs (NSAIDs) as the first choice for acute treatment, followed by combination preparations that include caffeine. Slider with three articles shown per slide. A doctor may prescribe stronger, narcotic pain relief medications for people with severe pleuritic pain. Google Scholar. A total of 194 studies including 735,006 participants worldwide were included in the analysis. The association of persistent symptoms such as fatigue, diffuse myalgia, and joint and musculoskeletal pain are all linked to mitochondrial dysfunction, oxidative stress, and reduced antioxidants [56]. "Long-haul COVID" refers to a condition where a person doesnt feel fully recovered from their illness, even months later, after the infection has resolved. J R Soc Med. Giorgio Sodero . Fatigue is most commonly prevalent among women of middle age and older patients [115]. Rabinovitch DL, Peliowski A, Furlan AD. Chronic pain conditions can be triggered by psychosocial stressors or organ-specific biological factors. 2022:d41586-022-01453-0. Instead, the person experiences discomfort in this part of the body as a result of soreness in the respiratory muscles and chest muscles. 2021. https://doi.org/10.1097/j.pain.0000000000002306. Therefore, you should never assume, even in children, that chest pain is a harmless symptom that will simply go away. 2). Post-COVID-19 pandemic has many characteristics that could potentially increase the prevalence of chronic pain, especially with stressors extending over many months [25, 30, 55]. 2020 Aug;46 Suppl 1:88-90. doi: 10.1016/j.semerg.2020.06.006. Geneva 2021. https://www.who.int/data/gho/publications/world-health-statistics. Thank you for your time and answers. COVID-19 may exacerbate preexisting pain or be associated with the appearance of new pain. 2021:19. Article After the procedure, the patient should be monitored in the same room. 2020;77(6):68390. .. Advertisement .. Coronavirus: Experiencing Chest Pain Post-Covid-19? Chronic pain patients may experience additional potential risk of functional and emotional deterioration during a pandemic, which can increase the long-term health burden [19, 20]. Clin Rev Allergy Immunol. Consult a doctor now! The following related keywords were used for the search (COVID-19, coronavirus and SARS-CoV-2, post-COVID pain, post-COVID pain syndromes, post-COVID headache, post-COVID chronic pain post-COVID neuropathic pain and post-COVID musculoskeletal pain). 2021;35(1):56-57. doi:10.1080/08998280.2021.1973274, Reardon S. Long COVID risk falls only slightly after vaccination, huge study shows. Patient weakness may contribute to rapid deconditioning and joint-related pain. b) Symptomatic treatment with pain killers and neuro muscular rehabilitation will help. A higher prevalence of musculoskeletal pain was also reported in non-hospitalized patients than hospitalized patients [61, 93]. Some common symptoms that occur alongside body aches are: pain in a specific part of the body. It facilitates the communications with those coming from long distances, physically unfit patients with multiple comorbidities, or already-infected patients [22, 117]. 2022;11:5569. https://doi.org/10.3390/jcm11195569. Pandemic-specific psychological and mental health burden [49,50,51,52]. COVID-19 rapid guideline: managing the long-term effects of COVID-19. J Headache Pain. Ayoubkhani D, Bermingham C, Pouwels KB, et al. Both act on lymphocytes by negatively modulating the response of natural killer cells. Moisset X, Moisset X, Bouhassira D, Avez Couturier J, Alchaar H, Conradi S, Delmotte MH, Lanteri-Minet M, Lefaucheur JP, Mick G, Piano V, Pickering G, Piquet E, Regis C, Salvat E, Attal N. Pharmacological and non-pharmacological treatments for neuropathic pain: systematic review and French recommendations. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Nonsteroidal anti-inflammatory drugs (NSAIDs), https://www.bhf.org.uk/informationsupport/conditions/angina, https://www.heart.org/en/health-topics/heart-attack/angina-chest-pain, https://www.health.harvard.edu/heart-health/angina-symptoms-diagnosis-and-treatments, https://www.covid19treatmentguidelines.nih.gov/overview/clinical-spectrum/, https://www.heart.org/en/news/2022/08/22/covid-19-infection-poses-higher-risk-for-myocarditis-than-vaccines, https://www.nhlbi.nih.gov/health/heart-inflammation/symptoms, https://www.nhlbi.nih.gov/health/heart-inflammation/treatment, https://www.nhlbi.nih.gov/health/heart-inflammation/types, https://www.ncbi.nlm.nih.gov/books/NBK558958/#_NBK558958_pubdet_, https://www.aafp.org/pubs/afp/issues/2007/0501/p1357.html, https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/coronavirus-and-your-health/long-covid, https://www.health.state.mn.us/diseases/coronavirus/pulseoximeter.html, https://www.nhs.uk/conditions/angina/treatment/, https://academic.oup.com/ehjcr/article/5/3/ytab105/6184571, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477961/, https://www.nhlbi.nih.gov/health/heart-inflammation. However, it can cause chest discomfort and pain. 2022;15:172948. J Pain Res. Since then, I have had these attacks of weakness and cannot work or often even take a walk. Kelly-Davies G. Why COVID infections leave some patients in chronic pain. The ICU management protocols add additional risk factors such as the use of neuromuscular block, corticosteroids and the risks of procedural pain such as intubation, tracheostomy, suction, cannulations, sampling, and catheterization. According to Dr. Gumrukcu, the most common symptoms of long COVID are fatigue, brain fog and memory issues, headaches, shortness of breath, chest pain, and cough. An increase in heart rate in and of itself is not horribly concerning, Altman said. This syndrome is characterized by a wide range of health problems including brain fog with cognitive disturbances, fatigue, dyspnea, myalgia and muscle weakness, depression, and persistent headaches [6]. 2) Post cardiovascular sequelae leading to myocarditis, percarditis or chronic pulmonary embolism. Interrupted care due to isolations and closing many services such as physiotherapy & supportive services. 2020;2(8):12003. A Word From Verywell (2022). Personal protection measures such as hand hygiene, face mask, and gloves during patient care, and cleaning of surfaces in the patient care environment should be taken according to the local regulations by healthcare authorities [16, 121]. Common symptoms include fatigue, shortness of breath, cognitive dysfunction, but also others, and generally have an impact on everyday functioning. Its also important to stay hydrated with three to four liters a day of fluid (unless you have heart failure) while avoiding alcohol and caffeine and modestly increasing salt intake (unless you have high blood pressure). Some of these symptoms can last for 3 months or longer. Patients with long COVID-19 present with a wide range of symptoms, ranging from mild to severe chest pain and tenderness. Article Salah N. El-Tallawy, Rohit Nalamasu, Christopher Gharibo, Kenneth Fiala, Joshua Martens & Alaa Abd-Elsayed, I. Putu Eka Widyadharma, Ni Nyoman Shinta Prasista Sari, Desak Ketut Indrasari Utami, Deepika Joshi, Vyom Gyanpuri, Neetu Rani Dhiman, Nhu Ngoc Nguyen, Van Thuan Hoang, Philippe Gautret, Sophie Juul, Niklas Nielsen, Janus Christian Jakobsen, Sadiye Murat, Bilinc Dogruoz Karatekin, Onur Incealtin, Pain and Therapy Vitamin D deficiency is pretty widespread and was made worse during the lockdowns. People stopped exercising, getting fresh air and sunshine, and socializing, which led to anxiety, depression, isolation, and fearfulness. Instead, it is not anxiety. Signs of depression and anxiety are frequently getting reported, along with sleeplessness and cognitive difficulties. Common Side Effects Side effects after a COVID-19 vaccination tend to be mild, temporary, and like those experienced after routine vaccinations. A significant number of patients infected with COVED-19 developed post- or long COVID-19 symptoms with more burden on patients with chronic pain. COVID-19 is also having a profound effect on chronic pain patients. Pain in the chest can be due to many reasons, but for a patient who has recovered from the deadly coronavirus infection, experiencing persistent chest pain can be a sign of . He has held positions with major news networks like NBC reporting on health policy, public health initiatives, diversity in medicine, and new developments in health care research and medical treatments. It is the most immediate way to enable physicians to continue treatment of patients. Development of new clinical practice guidelines for the diagnosis, management, medical and interventional pain therapy. CAS Taking a dosage of 50100 milligrams of indomethacin has shown positive effects on pain and lung function in studies on pleuritic pain. Open Forum Infect Dis. COVID-19 is having a profound effect on patients with chronic pain. Instead, the chest muscles and muscles that are necessary for breathing become sore, causing . COVID-19, nuclear war, and global warming: lessons for our vulnerable world. Chronic pain might affect up to 50% of the general population, while the prevalence of post-COVID-19 chronic pain was estimated to be 63.3% [29]. Pain can be an early symptom of acute COVID-19 infection, including sore throat, myalgias, back pain, and headache [28]. Persistent headache in patients with long COVID has a prevalence of 18%, is more prevalent in middle-aged women, and began 2weeks after the subsiding of respiratory symptoms [27, 69]. Ryabkova VA, Churilov LP, Shoenfeld Y. Neuroimmunology: what role for autoimmunity, neuroinflammation, and small fiber neuropathy in fibromyalgia, chronic fatigue syndrome, and adverse events after human papillomavirus vaccination? 2009;62:100612. Lancet. Brachial plexopathy after prone positioning. Cephalalgia. 2019;19:6192. COVID-19 Chest Pain. (2023). The following definitions can be used to differentiate different stages of both ongoing or post-COVID-19 signs and symptoms [1, 11, 12]. Although the acute stage of COVID-19 infection most commonly manifests with acute respiratory symptoms, one very common symptom of the disease is pain, while the most common symptoms of post-COVID syndrome are shortness of breath, dry cough, fatigue, loss of olfactory and gustatory function, tightness and chest pain, sleep and mood disturbances, body aches, muscle and joint pain, sore throat, fever, and persistent headaches. You also have the option to opt-out of these cookies. Results showed that 45% of COVID-19 survivors experienced a wide range of unresolved symptoms for at least 4months after COVID-19 infection [7]. An extensive computer search (from January 2020 to January 2023) was conducted including literature from the PubMed, Scopus, MEDLINE, Web of Science, and EMBASE databases. Eur J Intern Med. A cohort study of COVID-19-associated musculoskeletal symptoms. Clinical characteristics of coronavirus disease 2019 in China. These symptoms can feel worrying, especially if you already have a heart condition. Hong SM, Park YW, Choi EJ. Persistent glial activation and trigeminal-vascular activation are thought to play a role [72, 73]. More emphasis on program-directed self-management, rehabilitation, and physical therapy. That may be an easier way for the virus to get into the heart muscle, Altman said. After 12 weeks of symptoms Kerstin's GP referred her to a long Covid clinic. J Child Psychol Psychiatry. It leads to rapid and significant changes in the management of chronic pain and the medical practice in general. Pain Management in the Post-COVID EraAn Update: A Narrative Review, https://doi.org/10.1007/s40122-023-00486-1, Pain Management During the COVID-19 Pandemic, Pain as clinical manifestations of COVID-19 infection and its management in the pandemic era: a literature review, People living with HIV and the emerging field of chronic painwhat is known about epidemiology, etiology, and management, Neuropathic Pain Associated with COVID-19: a Systematic Review of Case Reports, Clinical patterns of somatic symptoms in patients suffering from post-acute long COVID: a systematic review, Interventions for treatment of COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING Project), Risk and clinical outcomes of COVID-19 in patients with rheumatic diseases compared with the general population: a systematic review and meta-analysis, Clinical presentations of pain in patients with COVID-19 infection, https://www.who.int/publications/m/item/weekly-epidemiological-update-on-COVID-19---4-january-2023, https://doi.org/10.1016/S0140-6736(20)31379-9, https://doi.org/10.1016/S1473-3099(21)00043-8, https://www.who.int/data/gho/publications/world-health-statistics, https://doi.org/10.1016/j.eclinm.2022.101762, https://doi.org/10.1007/s40122-020-00190-4, https://doi.org/10.1016/j.jclinepi.2009.06.005, https://www.nice.org.uk/guidance/ng188/resources/COVID19-rapid-guideline-managing-thelongterm-effects-of-COVID19-pdf-51035515742, https://www.who.int/standards/classifications/classification-of-diseases/emergency-use-icd-codes-for-COVID-19-disease-outbreak, https://www.england.nhs.uk/coronavirus/post-COVID-syndrome-long-COVID/, https://doi.org/10.1016/j.bpa.2020.07.001, https://doi.org/10.23736/S0375-9393.20.15029-6, https://iris.paho.org/bitstream/handle/10665.2/28414/9789275119037_eng.pdf?sequence=6&isllowed=y, https://doi.org/10.1016/j.bja.2020.05.021, https://doi.org/10.1080/00207411.2022.2035905, https://doi.org/10.1186/s10194-022-01450-8, https://doi.org/10.1093/pm/pnaa143.pnaa143, https://doi.org/10.1016/j.bja.2019.03.025, https://doi.org/10.1016/j.ejim.2021.06.009, https://doi.org/10.1097/j.pain.0000000000002564, https://doi.org/10.1016/j.bja.2020.06.003, https://doi.org/10.1007/s40122-021-00235-2, https://doi.org/10.1097/CCM.0000000000003347, https://doi.org/10.1007/s12016-021-08848-3, https://doi.org/10.1097/NNR.0000000000000565, https://doi.org/10.1038/s41591-021-01283-z, https://doi.org/10.1007/s10067-021-05942-x, https://doi.org/10.1038/s41580-021-00418-x, https://doi.org/10.1097/PR9.0000000000000885, https://doi.org/10.1097/j.pain.0000000000002306, https://doi.org/10.1001/jamanetworkopen.2021.28568, https://mhnpc.com/2021/05/18/COVID-triggers-increased-pain-management-needs/, https://doi.org/10.1038/s41541-022-00453-5, https://doi.org/10.1097/PR9.0000000000000884, http://creativecommons.org/licenses/by-ncnd/4.0/, https://doi.org/10.1016/j.heliyon.2022.e10148, https://doi.org/10.1007/s11916-022-01038-6, https://doi.org/10.1371/journal.pmed.1003773, https://doi.org/10.3389/fphys.2021.624154, https://doi.org/10.1016/j.jfma.2020.04.024, https://doi.org/10.3390/healthcare10122349, https://www.opensocietyfoundations.org/publications/lowering-threshold, https://www.uptodate.com/contents/COVID-19-evaluation-and-management-of-adults-with-persistent-symptoms-following-acute-illness-long-COVID#disclaimerContent, https://doi.org/10.1007/s00228-010-0879-1, https://doi.org/10.1016/j.jpainsymman.2012.08.013, https://doi.org/10.1038/s41598-022-24053-4, https://doi.org/10.1016/j.bbih.2022.100485, https://doi.org/10.1101/2022.11.08.22281807v1, http://creativecommons.org/licenses/by-nc/4.0/.

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